What it's used for
Estradiol may reduce hot flashes and night sweats.
TopicalHormone Therapy (HRT) · Topical
An individualized hormone regimen using cream and progesterone capsules; testosterone availability is limited to 30 states.
$299 · Month Supply 2mg/1mg/ml or 4mg/2mg/ml + 100mg, 150mg or 200mg
If testosterone is included as part of the treatment plan, it is only available in 30 states.
Ships to all states except AK, AL, AR, CT, DE, GA, HI, IA, IN, KS, MN, MO, MT, ND, NH, NM, OK, RI, SD, WY.
About this treatment
An individualized hormone regimen using cream and progesterone capsules; testosterone availability is limited to 30 states. Compounded medicines are not FDA approved or reviewed for safety, effectiveness, or quality before marketing.
The science
Estradiol can relieve selected menopausal symptoms, while progesterone helps protect the uterine lining when appropriately prescribed. Testosterone may be considered for selected desire concerns, but compounded female formulations have limited evidence.
Results depend on the formulation, route, and individual health factors. Evidence for an approved ingredient does not establish that a compounded product works the same way.
Benefits & evidence
Estradiol may reduce hot flashes and night sweats.
Appropriate progesterone helps protect the uterine lining.
Testosterone may help selected patients with low sexual desire.
Individual results vary and are not guaranteed.
Your next steps
Pick your treatment, plan length and state, then check out.
Share your health history and goals in a secure online form.
A licensed clinician reviews your intake, orders any required labs and decides if treatment is right for you.
If approved, your medication ships discreetly, with follow-up care along the way.
Safety information
Reported effects include breast tenderness, spotting, bloating, drowsiness, acne, and increased hair growth.
Discuss unexplained vaginal bleeding, hormone-sensitive cancer, liver disease, and a history of blood clots, stroke, or heart attack; avoid during pregnancy. Seek urgent care for chest pain, breathing trouble, or stroke symptoms. Prevent transfer of testosterone cream to others and discuss potentially irreversible voice or genital changes.
Compounded medications are prepared by a pharmacy for individual patients. They are not FDA approved and have not been reviewed by the FDA for safety or effectiveness.
Stop and contact your care team if you have a severe reaction. For a medical emergency, call 911.
Frequently asked questions
Follow the separate cream and capsule instructions. Do not omit progesterone unless your clinician changes the plan; testosterone access depends on your state.
Follow your clinician's review schedule. Contact them sooner for persistent side effects, worsening symptoms, or concerns about your response.
Follow the dispensing label for temperature, light protection, and discard dates. Ask your pharmacist before using medicine stored incorrectly.
Before starting: Estradiol, Progesterone, Testosterone (free & total), SHBG, CBC, CMP, Lipid panel,TSH, FT4, FT3. Follow-up: If testosterone is prescribed, follow up is at 12 weeks: Estradiol, Testosterone (free & total), CBC. At 1 year across the board, follow up: CMP, Lipids, Estradiol, Progesterone, Testosterone (free & total) Your clinician will tell you where and when to complete them.
It can ship to every state except Alaska, Alabama, Arkansas, Connecticut, Delaware, Georgia, Hawaii, Iowa, Indiana, Kansas, Minnesota, Missouri, Montana, North Dakota, New Hampshire, New Mexico, Oklahoma, Rhode Island, South Dakota, Wyoming.
Treatment is only prescribed when a licensed clinician decides it is appropriate. If it isn't, your care team will explain why and talk through other options.